中文ʻO Coronavirus Variant Strain 501Y-V2 o ʻApelika Hema
Ma Dekemaba 18, 2020, ua ʻike ʻo ʻApelika Hema i kahi mutant 501Y-V2 o ka coronavirus hou.I kēia manawa ua laha ka mutant ʻApelika Hema ma mua o 20 mau ʻāina.Ua hōʻike ʻia nā hoʻokolohua ma luna o ka New Corona-virus Mutants e lawe i nā ʻano ʻē aʻe ʻo New Coronavirus o K417N/T, E484K a me N501Y mutations e hiki ai ke hōʻemi i ka hiki ke hoʻokaʻawale i nā antibodies neutralizing plasma.Eia nō naʻe, ke hoʻohālikelike ʻia me ka genome Wuh01 (helu kaʻina MN908947), ʻo ka 501Y.V2 o ke kaʻina genome mutant ʻApelika Hema he 23 mau ʻano nucleotide.Loaʻa iā ia ka mutation N501Y like me ka British mutant B.1.1.7 sub-type, akā aia nō naʻe nā hoʻololi ʻana ma ʻelua mau kahua koʻikoʻi ʻo E484K a me K417N o ka protein S i loaʻa i nā hopena koʻikoʻi i ka hiki o ka maʻi maʻi.
ʻO ka New Coronavirus kahi maʻi maʻi RNA i hoʻopaʻa ʻia, a ʻoi aku ka nui o nā hoʻololi Genome.Hiki i ka ʻike maka hoʻokahi ke alakaʻi maʻalahi i ka ʻike ʻole ʻia o nā laʻana me ka haʻahaʻa viral haʻahaʻa a me nā maʻi virus mutated.ʻO ka helu o ka nānā hou ʻana i ka maikaʻi hoʻokahi i ka ʻike maka, hiki ke piʻi ma mua o 10%, hiki ke hoʻonui i ka hana a hoʻolōʻihi i ka manawa maʻi.Hiki ke hoʻonui i ka nui o ka ʻike a me ka hōʻoia like ʻana i nā hopena o kēlā me kēia pahuhopu.
Kiʻi 1. Kiʻi kiʻi kiʻi o ka mīkini maʻi Coronavirus hou
ʻO ka Coronavirus Mutant B.1.1.7 hou o Pelekane
Ma ka lā 26 o Dekemaba, 2020, ua paʻi ʻia ka pepa ʻepekema mua o ka B.1.1.7 Strain ma ka pūnaewele.Ua hōʻoia ka Institute of Hygiene University of London UK and Tropical Diseases, ʻoi aku ka hiki i ka B.1.1.7 Strain ke hoʻolaha ma mua o nā maʻi ʻē aʻe, ʻoi aku ia ma mua o 56% (95% CI 50-74%).No ka mea ʻoi aku ka ikaika o ka hoʻouna ʻana i kēia ʻano mutant hou, ua lilo ia i mea paʻakikī loa e kāohi i ka COVID-19.I ka lā aʻe, ua hoʻouka ke Kulanui o Birmingham ma United Kingdom i kahi ʻatikala ma MedRxiv.Ua ʻike ʻia ka haʻawina ua hoʻonui nui ʻia ka helu o ORF1ab a me N virus gene i nā maʻi i loaʻa i ka maʻi mutant B.1.1.7 (S-gene dropout);ua nānā ʻia kēia hanana i ka heluna kanaka.Hōʻike kēia ʻatikala i nā mea maʻi i loaʻa i ka mutant B.1.1.7 o Beretania he ʻoi aku ka kiʻekiʻe o ka viral load, no laila e ʻoi aku ka pathogenic o kēia mutant.
Kiʻi 2. ʻO ka genome mutation sequence i loko o ka coronavirus mutant strain B.1.1.7 o Pelekane.
Kiʻi 3. Ua loaʻa ka mutation N501Y ma Pelekane a me ʻApelika HemaNā ʻano like ʻole
ʻO ka pahu ʻike o nā ʻano ʻano Coronavirus hou
Ua hoʻomohala maikaʻi ʻo Chuangkun Biotech Inc. i kahi pahu ʻike no ka B.1.1.7 a me 501Y-V2 mau ʻano coronavirus hou.
ʻO nā mea maikaʻi o kēia huahana: ʻike kiʻekiʻe, ʻike like ʻia o 4 mau pahuhopu, e uhi ana i nā kahua mutation nui o B.1.1.7 mutant strain a me 501Y.V2 South Africa mutant strain.Hiki i kēia kit ke ʻike i nā pūnaewele mutation N501Y, HV69-70del, E484K a me ka gene coronavirus S hou;Ho'āʻo wikiwiki: 1 hola 30 mau minuke wale nō mai ka hōʻiliʻili laʻana a hiki i ka hopena.
Kiʻi 4. ʻIke ʻia o COVID-19 Beretania ʻano ʻokoʻa Amplification Curve
Kiʻi 5. ʻIke ʻia o COVID-19 South Africa Variant Amplification Curve
Kiʻi 6. ʻAno ʻāhiu o New coronavirus amplification curve
ʻAʻole maopopo ia pehea e hōʻiliʻili ai kēia mau mutations i ka hopena lōʻihi o ka maʻi maʻi COVID-19 pololei.Akā, hoʻomanaʻo mai kēia iā mākou e pili ana kēia mau hoʻololi i ka hopena o ka pale kūlohelohe a me ka pale ʻana i lawe ʻia e ka lāʻau lapaʻau.Hoʻomanaʻo mai ia iā mākou pono mākou e nānā mau i ka coronavirus hou no ka manawa lōʻihi a hoʻonui i ka kano COVID-19 e hoʻoponopono ai i ka ulu ʻana o ka coronavirus hou.
Ka manawa hoʻouna: Mar-12-2021